Dr. Andrew D. Westwell is currently Reader in Medicinal Chemistry at the School of Pharmacy and Pharmaceutical Sciences at Cardiff University (UK), having worked in Cardiff since 2006. He received his BSc (Hons) in Chemistry and PhD in organic chemistry at the University of Leeds (UK). Following a postdoctoral fellowship at Loughborough University (UK), he joined a Cancer Research UK Programme at the University of Nottingham (UK), initially as Senior Research Fellow, later as Lecturer. Following his move to Cardiff he has established a number of collaborative research projects focusing on breast cancer drug discovery, new synthetic chemistry methods, and cancer imaging by Positron Emission Tomography (PET). He has recently been a joint scientific founder of Tiziana Life Sciences (www.tizianalifesciences.com), taking research and IP generated at Cardiff University into a commercial setting, culminating in the launch of a London AIM-listed company progressing a new anti-metastatic drug candidate through pre-clinical evaluation.
He has published more than 100 journal articles and reviews. Technology transfer activities have included a number of patent filings, and he was previously lead chemist in Nottingham on the development of a new molecule from discovery at the bench to early clinical evaluation in cancer. He currently serves on the Editorial Board of the international journal Future Medicinal Chemistry.
Annmarie is the lead for our Palliative and Supportive Care Work Package and is the academic lead for the Centre’s Patient and Public Involvement work.
She is Scientific Director of the Marie Curie Palliative Care Research Centre, which has a strong historical and ongoing link with the Wales Cancer Trials Unit. Previously, she was acting Scientific Lead for palliative care clinical trials at the WCTU, and continues to coordinate the palliative care portfolio, with colleague Dr Anthony Byrne, also acting as qualitative research lead and Patient and Public Involvement lead for the unit. She is an honorary lecturer on the MSc Palliative Medicine course based at Cardiff University, acting as supervisor to students undertaking qualitative research projects.
Studies are adopted to the MCPCRC portfolio on the basis that rapid changes to care will ensue as a result.
Annmarie is interested in complex interventions and the patient experience at all levels, including the impact of trial processes and interventions with regard to issues of equipoise and effectiveness, as well as difficult areas of treatment decision-making in advanced cancer, and also late effects of treatment. She has developed a portfolio of qualitative studies embedded within oncology and supportive care clinical trials and national and international multicentre qualitative studies.
On the basis of the clinical trials portfolio, she is working towards synthesising the datasets to explore crosscutting themes relating to trial conduct, e.g. understandings of equipoise, motivations to participate in trials, (mis)understandings of trials treatments and processes etc.
Dr Awen Gallimore gained a DPhil in Professor Andrew McMichael's laboratory in Oxford, studying the anti-viral role of cytotoxic T cells in SIV infection, subsequently moving to Professor Rolf Zinkernagel's laboratory to study the correlates of anti-viral immunity. The recent focus of the Gallimore lab however has been on the regulation of anti-tumour immune responses. This has resulted in a body of work detailing the impact of regulatory T cells on tumour development in both mice and humans. The aim of the group therefore is to take basic research using models of cancer through to testing novel immunotherapies in cancer patients. Recent findings indicate that Tregs can direct specialized vascular differentiation in tumours resulting in T-cell recruitment and cancer rejection. These studies open doors for novel avenues of immunotherapy.
David is Professor of Health Informatics at Swansea University’s Medical School, where he is Deputy Director of Farr-CIPHER – one of the four UK Centres of Excellence for E-Health Research, funded by a consortium of top UK research funders led by the MRC, as part of the Farr Institute. He is also Principal investigator and Director of the Administrative Data Research Centre Wales (ADRCW), an £8million investment into Wales by the ESRC as part of its Big Data initiative.
David is joint lead of the SAIL Databank, an internationally recognised data linkage resource that safely and securely share linked and carefully de-identified data from a wide variety of routinely collected data from across Wales, and which supports a wide range of researchers from across the UK and internationally.
David is Director of the eHealth Industries Innovation (ehi2) Centre, developing links between academia, the NHS, and business within the UK and internationally. He is also University Director of NHS Wales Informatics Research Laboratories, created through a collaboration between Swansea University and NHS Wales Informatics Service, the national programme for NHS IT for Wales. David is a Fellow of the Royal Society for the Encouragement of the Arts, Manufactures and Commerce (FRSA) and past Chairman and a current Director of MediWales, a membership organisation representing the medical technology sector of Wales. He is a member of numerous committees and national bodies relating to health informatics and health-related research. He has received research grants and consultancy contracts valuing over £45m over recent years.
James is co-lead of the work package for Trials through to Practice for the Wales Cancer Research Centre. James is Consultant Clinical Oncologist specialising in Neuro-Oncology and Lung cancer based at Velindre Cancer Centre, Cardiff. He completed a PhD at Cardiff University Institute of Cancer Genetics in 2014. His research interest is in Neuro-Oncology, in particular investigating novel imaging methods in adults with brain tumours. He has led the first Oncology research collaboration with the Cardiff University Brain Research Imaging Centre (CUBRIC) in Cardiff using technical MRI to investigate the effects of radiotherapy on cognitive function in patients with secondary brain tumours. He is also interested in developing technical radiotherapy for adults with Glioma and in studying how advanced MRI methods may be used in radiotherapy planning for brain tumours.
He is the clinical and research lead in Neuro-Oncology at Velindre Cancer Centre and is a member of the Glioma subgroup of the National Cancer Research Institute (NCRI) Brain Clinical Studies Group. He has developed clinical trial activity in Cardiff, improving access to clinical trials for patients with brain tumours in Wales. He is the lead local investigator for several brain tumour trials and sits on the trial management group of national trials in Neuro-Oncology.
Jim has a background of working in education and social services. In 2007 he joined the Involving People Advisory Group as a volunteer. In his voluntary career he has been involved in the Wales Cancer Trials Unit (WCTU) and Marie Curie Palliative Care Research Centre (MCPCRC)Trial Management and Study Groups. From from 2011 – 2014 he acted as Marie Curie's and WCTU’s Research Partner Coordinator.
He is an active contributor to Public Health Wales and Health & Care Research Wales. In 2015 he was made an Honorary Research Associate at Cardiff University’s School of Cancer and Genetics.
Jim has also worked on projects with Tenovous, Velindre NHS Trust and the Welsh Government. He plays a key role in the involvement of patients and the public in the Centre’s work.
Jodie Bond is a communications professional with a background working in research, the arts, the third sector and education. She joined the Wales Cancer Research Centre in 2015 when the organisation was in its infancy and has developed the Centre’s engagement activity, brand and reputation from scratch.
Jodie believes that through tailoring communications and engagement activities, we can help the public develop a greater understanding and appreciation of research and its impact on society. She knows how to catch the public’s interest, promote sell-out events, and influence stakeholders — and it’s not just keeping up to date with the latest developments on social media. It’s how much you value, and how well you connect with, the individuals you’re reaching out to.
Jodie has managed a number of successful communications and marketing campaigns. She has promoted sell-out international tours for the UK’s leading contemporary circus, managed multi-regional PR campaigns for the UK’s second largest charity, and worked as part of a team who won gold at the CIPR Cyrmu awards.
She holds a degree in Creative Writing and Video Production from Buckinghamshire New University.
Julie retired from her post as Deputy Director of Cardiff University Careers Service in December 2013, having spent 26 years in this field. Prior work experience included science teaching in secondary and further education and a period of three years early in her career in hospital management.
Her degree was in Physiology and Biochemistry and she has always been interested in health, health related research and the NHS. Some experiences of ill health in recent years meant that Julie became a frequent user of the NHS, which in turn meant that she had something to offer the Involving People Network, by feeding in the patient viewpoint to clinical research. She is currently a member of four Trial Management Teams for research projects, two Steering Groups, an All Wales Research Funding Prioritisation Panel (AWPP), and a NICE Committee on Diagnostic Services.
She hopes that my previous and current experiences will be an excellent background to enable me, as a member of the public, to contribute effectively as a Theme Research Partner for the Wales Cancer Research Centre.